Behavioral Health
The stress of experiencing homelessness can amplify previous mental illness and trigger anxiety, depression, fear, substance use, and sleeplessness.
UCSF BHHI behavioral health research focuses on people’s access to permanent housing, mental health services, shelters, and substance abuse support to prevent and end homelessness in the United States.
Related Resources
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Our Research
Contingency Management for Smoking Cessation Among Adults Experiencing Homelessness
August 11, 2026
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Our Research
Attitudes toward tobacco-free and cannabis-free policies among residents in permanent supportive housing who use tobacco, cannabis, and other substances
Maya Vijayaraghavan
April 15, 2026
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Our Research
Attitudes toward tobacco-free and cannabis-free policies among residents in permanent supportive housing who use tobacco, cannabis, and other substances
Maya Vijayaraghavan
April 15, 2026
Over 60% of permanent supportive housing (PSH) residents smoke cigarettes, and over 50% use cannabis. Co-use of tobacco and cannabis may be linked with other substance use. We explored attitudes toward tobacco-free and cannabis-free policies among PSH residents who smoked cigarettes, co-used tobacco and cannabis, or other substances.
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Our Research
Syndemic lives of women who smoke and experience homelessness: secondary analysis of US qualitative data
January 9, 2026
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Our Research
Syndemic lives of women who smoke and experience homelessness: secondary analysis of US qualitative data
January 9, 2026
Tobacco use remains the leading cause of preventable deaths worldwide. Despite efforts by many countries to reduce the impact of tobacco products and lower smoking rates, smoking prevalence is higher among people experiencing homelessness. The reasons are complex and go beyond individual choices, including limited awareness about quitting, restricted access to services, and previous negative experiences.
Using the SEM framework, which emphasizes the policy and environmental contexts, this study offers a deeper understanding of the context of the lives women experiencing homelessness. The evidence from this study supports the implementation of gender- and age-appropriate holistic approaches to healthcare and tobacco interventions tailored to this community.
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Our Research
Methodological Lessons Learned From a Longitudinal Study of Overdose Vulnerability Among People Experiencing Homelessness Who Co-use Fentanyl and Stimulants in San Francisco, CA, USA
November 26, 2025
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The U.S. overdose crisis is now driven by polysubstance use involving fentanyl and stimulants. We received funding through the National Institutes on Drug Abuse’s Helping to End Addiction Long-Term (HEAL) initiative to conduct longitudinal qualitative research on polysubstance use among people experiencing homelessness (PEH) in San Francisco, California. This paper discusses the rationale for these combined approaches and lessons learned from conducting longitudinal qualitative research with a community in real-time during enhanced risk for criminalization and overdose fatality.
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